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Withdrawal from oxycodone is probably going to happen to Individuals who have taken oxycodone consistently or misused oxycodone. Frequent signs or symptoms of withdrawal consist of:

Misuse and abuse of OXYCONTIN boosts hazard of overdose, which can lead to central anxious method and respiratory depression, hypotension, seizures, and death. The danger is amplified with concurrent abuse of OXYCONTIN with Alcoholic beverages and/or other CNS depressants.

The concomitant usage of OXYCONTIN and CYP3A4 inducers can reduce the plasma concentration of oxycodone [see CLINICAL PHARMACOLOGY], resulting in diminished efficacy or onset of the withdrawal syndrome in individuals that have created physical dependence to oxycodone [see WARNINGS AND PRECAUTIONS].

Expecting or planning to become Expecting. Usage of OXYCONTIN for an extended timeframe for the duration of pregnancy can cause withdrawal signs in your new child toddler that could be existence-threatening if not identified and handled.

Usage of higher commencing doses in individuals that are not opioid tolerant could cause fatal respiratory depression [see WARNINGS AND Safety measures].

OXYCONTIN® exposes individuals and various people on the threats of opioid addiction, abuse, and misuse, which can lead to overdose and Demise.

People at elevated possibility can be prescribed opioids which include OXYCONTIN but use in these types of people necessitates intense counseling about the threats and appropriate use of OXYCONTIN as well as frequent reevaluation for indications of addiction, abuse, and misuse. Take into consideration prescribing naloxone for your crisis therapy of opioid overdose [see DOSAGE AND ADMINISTRATION and Daily life-Threatening Respiratory Despair].

People at substantial hazard of OXYCONTIN abuse include things like People oxycontin using a historical past of extended utilization of any opioid, which includes products made up of oxycodone, All those using a history of drug or alcohol abuse, or those that use OXYCONTIN in combination with other abused medications.

Be sure you know how to just take oxycodone and what other prescription read more drugs you must prevent using with it. See also Drug Interactions part. Get health care help without delay if any of such extremely major Unwanted side effects come about: slow/shallow respiration, uncommon lightheadedness, intense drowsiness/dizziness, difficulty waking up.

Go over The provision of naloxone to the emergency treatment method of opioid overdose With all the affected person and caregiver and assess the potential require for access to naloxone, the two when initiating and renewing treatment with OXYCONTIN [see WARNINGS AND Safety measures].

As a guideline for Grownups, the overall every day oxycodone dosage typically could be enhanced by 25% to 50% of the current overall daily dosage, every time a boost is clinically indicated.

This medication may well interfere with sure lab exams (which include amylase/lipase concentrations), possibly causing Untrue take a look at success. Be certain lab more info personnel and all your Health professionals know you utilize this drug.

Remember that this medication continues to be prescribed because your physician has judged that the gain to you is bigger than the potential risk of Unwanted effects. Lots of people working with this medication do not need severe Negative effects.

FDA-authorised indications may well differ for various oxycodone types and strengths. Check the product or service deal insert for indications and utilization for every solution.